Lead/Drug Discovery from Natural Resources

Lead/Drug Discovery from Natural Resources

Blog Article

Natural products and their derivatives have been shown to be effective drug candidates against various diseases for rumchata proof many years.Over a long period of time, nature has produced an abundant and prosperous source pool for novel therapeutic agents with distinctive structures.Major natural-product-based drugs approved for clinical use include anti-infectives and anticancer agents.

This paper will review some natural-product-related potent anticancer, anti-HIV, antibacterial and antimalarial drugs or 5326058hx lead compounds mainly discovered from 2016 to 2022.Structurally typical marine bioactive products are also included.Molecular modeling, machine learning, bioinformatics and other computer-assisted techniques that are very important in narrowing down bioactive core structural scaffolds and helping to design new structures to fight against key disease-associated molecular targets based on available natural products are considered and briefly reviewed.